CD7 anticorps

N° du produit ABIN120616

Cet anticorps Souris Monoclonal détecte spécifiquement CD7 dans FACS, WB, IP et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour CD7 anticorps (ABIN120616)

Antigène: CD7

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD7 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MEM-186

Détail du produit anti-CD7 anticorps

Specificité: The antibody reacts with CD7, a 40 kDa type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Precipitation methods and ion exchange chromatography

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Human acute myelogenous leukaemia cell line KG-1

Isotype: IgG1

Information d'application

Indications d'application: Immunoprecipitation. Flow Cytometry. Western Blotting under non reducing conditions. Immunohistochemistry (paraffin sections): Recommended dilution: 5 m g/mL, Positive tissue: spleen
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Détails sur CD7

Antigène: CD7

Autre désignation: CD7

Sujet: CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.Synonyms: GP40, Leu-9, T-cell leukemia antigen, TP41

ID gène: 924

UniProt: P09564

Pathways: Cell-Cell Junction Organization